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Puritan's Pride, SAM-e, 400 mg, 60 Caplets EnergySupport Play up natural assets withProduct Description SAM e is a vital substance that's found in most of your cells and is essential to many biochemical reactions in the body. Because of that, it serves many roles including promoting joint comfort and liver health but it's worth noting that SAM e can support emotional well being as well.* Discovered by Italian scientist Giulio Cantoni in 1952, SAM e has been used extensively in Europe for more than 20 years. SAM e may play a role in